Dengfeng Guan

This paper introduces Asset, a tool to evaluate genome assemblies using long-range data, demonstrating its ability to detect structural misassemblies in human, goat, and fish genomes.

The paper summarizes methods and lessons from assembling 16 vertebrate genomes, highlights the importance of long-read sequencing, and introduces the Vertebrate Genomes Project to generate complete reference genomes for all vertebrate species.

The paper introduces a tool to identify and remove haplotypic duplication in genome assemblies, improving continuity and completeness.

deSPI classifies metagenomic reads using a lightweight de Bruijn graph-based reference index, achieving faster speed and comparable accuracy.