Author

Matteo Boccalini

Centre National de la Recherche ScientifiqueORCID 0000-0002-6392-4978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandro BarducciiD· 2 shared Matteo PaloniiD· 2 shared Davide ErbaiD· 1 shared Giovanni BussiiD· 1 shared Yelyzaveta BerezovskaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersBiophysics

Alessandro BarducciORCID

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2 papers

Recent·Most cited

Interplay Between Protein-RNA Binding and Phase Separation Drives Emergent Behavior in RNP Condensates

Matteo Boccalini, Davide Erba, Matteo Paloni, Alessandro Barducci

The paper develops a model showing how protein-RNA binding and phase separation interact to influence RNP condensate behavior, revealing RNA's role as a scaffold and explaining condensation dynamics.

bioRxiv · Jun 25, 2026 · PreprintBiophysics

Exploring RNA destabilization mechanisms in biomolecular condensates through atomistic simulations

Matteo Boccalini, Yelyzaveta Berezovska, Giovanni Bussi, Matteo Paloni, Alessandro Barducci

This study uses atomistic simulations to show that RNA structure is destabilized in biomolecular condensates due to interactions with peptides, with amino acid composition affecting RNA conformation.

Proceedings of the National Academy of Sciences · Apr 9, 2025Peer-reviewedBiophysics