BiophysicsNature CommunicationsPeer-reviewed
Structural basis of SIRT7 nucleosome engagement and substrate specificity
Carlos Moreno–Yruela, Babatunde Ekundayo, Polina N. Foteva…·Beat Fierz
This study determines the structural basis of SIRT7's specificity for H3K36 and H3K18 deacylation by solving nucleosome-bound SIRT7 structures and analyzing enzyme-nucleosome interactions.
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