Author

Masao Ôta

Shinshu UniversityORCID 0000-0002-6400-5658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

Masayuki HanaokaiD· 2 shared Nobumitsu Kobayashi· 2 shared Yoshiaki KitaguchiiD· 2 shared Yunden DromaiD· 2 shared Buddha BasnyatiD· 1 shared Fengming YueiD· 1 shared Masanori YasuoiD· 1 shared Shuhei Nozawa· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersGenetics

Masayuki HanaokaORCID

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2 papers

Recent·Most cited

Downregulations of mRNA expressions in the EPAS1and EGLN1: Unraveling a genetic mechanism for high-altitude hypoxia adaptation in Sherpa highlanders

Yunden Droma, Fengming Yue, Masao Ôta, Nobumitsu Kobayashi, Yoshiaki Kitaguchi, Masayuki Hanaoka

This study investigates mRNA expression levels of EPAS1 and EGLN1 in Sherpa highlanders and lowlanders, finding lower expressions in Sherpa highlanders and associations with specific SNPs that may contribute to hypoxia tolerance.

bioRxiv · May 23, 2024 · PreprintGenetics

Hypoxia-tolerant vascular endothelial growth factor-A (VEGF-A) and the genetic variations of VEGFA in Sherpa highlanders

Yunden Droma, Takumi Kinjo, Shuhei Nozawa, Nobumitsu Kobayashi, Masanori Yasuo, Yoshiaki Kitaguchi, Masao Ôta, Buddha Basnyat, Masayuki Hanaoka

This study examines VEGF-A levels and genetic variations in Sherpa highlanders and non-Sherpa lowlanders, finding no hypoxia response in Sherpas and significant genetic differences in VEGFA SNPs.

bioRxiv · Mar 16, 2020 · PreprintGenetics