Emily Olfson

A genomic study of trichotillomania and excoriation disorder in families

This study investigates the genetic architecture of trichotillomania and excoriation disorder using genome-wide array data from 110 families, finding significant polygenic risk for OCD and rare CNVs in neurodevelopmental genes.

Ultra-rare de novo damaging coding variants are enriched in attention-deficit/hyperactivity disorder and identify risk genes

This paper identifies ultra-rare de novo damaging variants in ADHD cases and finds KDM5B as a high-confidence risk gene, along with enriched biological pathways.

Primary complex motor stereotypies are associated with de novo damaging DNA coding mutations that identify candidate risk genes and biological pathways

The paper identifies de novo damaging DNA mutations in CMS patients, linking them to risk genes and biological pathways related to motor stereotypies.