Gwyneth C. Zai

Ultra-rare de novo damaging coding variants are enriched in attention-deficit/hyperactivity disorder and identify risk genes

This paper identifies ultra-rare de novo damaging variants in ADHD cases and finds KDM5B as a high-confidence risk gene, along with enriched biological pathways.

Genome-wide Association Study of Pediatric Obsessive-Compulsive Traits: Shared Genetic Risk between Traits and Disorder

This study identifies a genome-wide significant variant for OC traits and shows shared genetic risk between OC traits and OCD.

Examination of the Shared Genetic Basis of Anorexia Nervosa and Obsessive-Compulsive Disorder

This study investigates the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder using a cross-disorder GWAS, finding a significant genetic correlation and associations with psychiatric and metabolic traits.

De novo damaging coding mutations are strongly associated with obsessive-compulsive disorder and overlap with autism

The paper identifies de novo damaging mutations in OCD and finds overlap with autism genes, suggesting shared genetic risk.