Author

Lei Zhang

Anhui UniversityORCID 0000-0002-6447-2053Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lei Zhang18 papers · University of Minnesota

Biology Disciplines

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Bioinformatics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein structure prediction· 2 Approach:experimental assay· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Dong SiiD· 2 shared Jie HouiD· 2 shared Renzhi CaoiD· 2 shared Bo JiangiD· 1 shared Hailey Ledenko· 1 shared Jinxiu Zhao· 1 shared Junyong ZhuiD· 1 shared Ke XuiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioinformatics

Dong SiORCID

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3 papers

Recent·Most cited

GOBoost: Leveraging Long-Tail Gene Ontology Terms for Accurate Protein Function Prediction

Lei Zhang, Yang Wang, Xiao Chen, Jie Hou, Dong Si, Rui Ding, Bo Jiang, Hailey Ledenko, Renzhi Cao

GOBoost improves protein function prediction by addressing long-tail distribution of Gene Ontology Terms using an ensemble strategy and specialized loss functions.

Bioinformatics · Jun 1, 2025Peer-reviewedBioinformatics

Development of an ELISA assay for EV quantification to assist the large-scale EV manufacture

Xin Zhou, Wenli Wang, Lei Zhang, Shiyi Yang, Xincheng Peng, Xin Zhang, Jinxiu Zhao, Xinjun He, Ke Xu

This paper develops an ELISA assay for EV quantification to improve accuracy in large-scale EV manufacturing by reducing interference from contaminants.

bioRxiv · Oct 31, 2024 · PreprintBiochemistry

AnglesRefine: refinement of 3D protein structures using Transformer based on torsion angles

Lei Zhang, Junyong Zhu, Sheng Wang, Jie Hou, Dong Si, Renzhi Cao

AnglesRefine refines 3D protein structures using a Transformer model focused on torsion angles, improving model quality and reducing computational time.

IEEE Transactions on Computational Biology and Bioinformatics · Jul 3, 2024Peer-reviewedBioinformatics