G-protein coupled receptor 88 knock-down in the associative striatum reduces the psychiatric symptoms in a translational model of Parkinson’s disease
Benjamin Galet, Manuela Ingallinesi, Jonathan Pegon, Anh N. Do Thi, Philippe Ravassard, Nicole Faucon Biguet, Rolando Meloni
This study shows that knocking down GPR88 in the associative striatum of a rat PD model reduces psychiatric symptoms by modulating Rgs4 and ΔFosB.
bioRxiv · Apr 24, 2019 · PreprintNeuroscience