Unmasking Glycoforms: Lectin-Based Profiling and Functional Implications of Targeted Glycosylation Knockouts in CHO Cells
Cristina Abascal Ruiz, Sheryl Li Yan Lim, Jacobus Brink, Sara Carillo, Eoin Casey, Jonathan Bones, Ioscani Jiménez del Val
This study evaluates lectin-based surface profiling as a predictor of mAb product glycosylation in CHO cells following targeted glycogene engineering.
bioRxiv · May 13, 2026 · PreprintCell Biology