Author

Sara Carillo

National Institute for Bioprocessing Research and TrainingORCID 0000-0002-5943-8993Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ioscani Jiménez del ValiD· 3 shared Jonathan BonesiD· 3 shared Apostolos TsopanoglouiD· 2 shared Itzcóatl A. Gómez· 2 shared Mina GhahremanzamanehiD· 2 shared Alfonso BlancoiD· 1 shared Brian GlennoniD· 1 shared Cristina Abascal RuiziD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBioengineering

Ioscani Jiménez del ValORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Next-gen glycoengineering: combining cellular and metabolic engineering to fine tune mAb β1,4-galactosylation

Apostolos Tsopanoglou, Mina Ghahremanzamaneh, Itzcóatl A. Gómez, Kallum Doyle, Brian Glennon, Sara Carillo, Jonathan Bones, Ioscani Jiménez del Val

This paper combines metabolic and cellular glycoengineering to control mAb β1,4-galactosylation, achieving broad tunable control and improved pharmacological activity.

bioRxiv · Sep 28, 2026 · PreprintBioengineering

Computationally inspired glycoengineering to maximise mAb β4-galactosylation

Itzcóatl A. Gómez, Mina Ghahremanzamaneh, Apostolos Tsopanoglou, Alfonso Blanco, Sara Carillo, Jonathan Bones, Ioscani Jiménez del Val

This paper describes a dual genetic engineering strategy to enhance mAb β4-galactosylation in CHO cells, achieving over 90% galactosylation and reducing Man5 glycans without affecting mAb titre.

Metabolic Engineering · Sep 7, 2026Peer-reviewedBioengineering

Unmasking Glycoforms: Lectin-Based Profiling and Functional Implications of Targeted Glycosylation Knockouts in CHO Cells

Cristina Abascal Ruiz, Sheryl Li Yan Lim, Jacobus Brink, Sara Carillo, Eoin Casey, Jonathan Bones, Ioscani Jiménez del Val

This study evaluates lectin-based surface profiling as a predictor of mAb product glycosylation in CHO cells following targeted glycogene engineering.

bioRxiv · May 13, 2026 · PreprintCell Biology