Author

Giorgio Roberto Merlo

University of TurinORCID 0000-0002-6478-0486Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Aurora SavinoiD· 2 shared Carla LiaciiD· 2 shared Lidia AvalleiD· 2 shared Valeria PoliiD· 2 shared Francesco IorioiD· 1 shared Ilaria BertaniiD· 1 shared Lucia Prandi· 1 shared Mattia CameraiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Aurora SavinoORCID

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2 papers

Recent·Most cited

Psychedelic Hormesis: LSD Activates Adaptive Stress Transcriptional Programs in the Prefrontal Cortex

Aurora Savino, Carla Liaci, Giorgio Roberto Merlo, Lucia Prandi, Lidia Avalle, Valeria Poli

This study shows LSD induces adaptive stress transcriptional programs in the prefrontal cortex of mice, aligning with hormetic adaptation rather than chronic stress.

bioRxiv · Sep 18, 2026 · PreprintMolecular Biology

Lysergic acid diethylamide reverses aging- and neurodegeneration-associated brain transcriptional programs

Aurora Savino, Carla Liaci, Ilaria Bertani, Simona Rando, Mattia Camera, Giorgio Roberto Merlo, Lidia Avalle, Valeria Poli, Nereo Kalebic, Francesco Iorio

This study shows that LSD induces gene expression patterns opposing aging and neurodegeneration in the brain, suggesting potential therapeutic effects through transcriptional reversal.

bioRxiv · May 29, 2026 · PreprintNeuroscience