Engineering tunable synthetic fibrotic niches to model acinar-to-ductal metaplasia in 2D pancreatic culture systems
Shanmukha S Ayyalasomayajula, Jennifer P. Morton, Catherine Cecilia Berry, Matthew Walker
This paper develops a 2D hydrogel platform to study how mechanical and biochemical cues influence acinar-to-ductal metaplasia in pancreatic cells.
bioRxiv · Oct 16, 2026 · PreprintCancer Biology