Matthew Walker

This paper develops a 2D hydrogel platform to study how mechanical and biochemical cues influence acinar-to-ductal metaplasia in pancreatic cells.

This study shows that viscosity, not just elasticity, drives EMT in pancreatic intraepithelial neoplasia using hydrogel models.

The paper develops a synthetic BM niche model to test CRISPR-CAR T-cell therapy for AML, showing its efficacy in a human-like environment.

This study identifies biomechanical compartmentalization in the regenerating intestine and shows vascular Piezo1 influences angiogenesis and stem cell proliferation across species.