Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
John K. Mich, Lucas T. Graybuck, Erik E. Hess, Joseph T. Mahoney, Yoshiko Kojima, Yi Ding, Saroja Somasundaram, Jeremy A. Miller, Brian E. Kalmbach, Cristina Radaelli, Bryan B. Gore, Natalie Weed, Victoria Omstead, Yemeserach M. Bishaw, Nadiya V. Shapovalova, , Boaz P. Levi
The paper identifies enhancer elements that drive subclass-specific gene expression in neocortex across mouse, primate, and human species using comparative epigenetics and AAV-based functional assays.
Cell Reports · Jan 1, 2020Peer-reviewedNeuroscience