Klementina Fon Tacer

This study shows that MAGEA3/6 proteins in pancreatic cancer cells enhance metabolic flexibility by regulating glycolysis and mitochondrial metabolism, revealing therapeutic vulnerabilities.

This study shows GD3S deficiency disrupts NKA and PMCA function in mouse brain by altering ganglioside and lipid raft composition, suggesting therapeutic potential through exogenous ganglioside administration.

This study investigates the impact of Magel2 loss on pituitary translation in a mouse model of PWS and SYS, revealing translatomic alterations and their functional implications.

This study investigates the assembly mechanism of the USP7/MAGEL2 complex and identifies mutations that disrupt its formation, linking it to neurodevelopmental diseases.

This study compares mitochondrial ultrastructure and metabolism between glioblastoma stem-like cells and differentiated cells before and after temozolomide treatment, finding differences in mitochondrial morphology and metabolic dependence.

This study identifies MAGE antigens as markers of tumor heterogeneity and species-specificity in group 3 medulloblastoma, showing their role in cell survival and potential as therapeutic targets.