PPP1R3G Deletion Blocks RIPK1-Mediated Apoptosis and Necroptosis in Doxorubicin-Induced Cardiotoxicity
Xueling Ma, Ken Chen, Zhigao Wang
This study identifies PPP1R3G as a critical amplifier of doxorubicin-induced cardiotoxicity by promoting RIPK1-mediated apoptosis and necroptosis.
Proceedings of the National Academy of Sciences · Apr 15, 2026Peer-reviewedMolecular Biology