BiophysicsThe Journal of Chemical PhysicsPeer-reviewed
AT vs. GC binding of protamine-template: A microscopic understanding through molecular dynamics and binding free energies
Sandip Mandal, Khadka Bahadur Chhetri, Yun Hee Jang…·Prabal Kumar Maiti
This study uses molecular dynamics simulations to show that a protamine-mimicking peptide binds preferentially to GC-rich sequences in the major groove and AT-rich sequences in the minor groove of DNA.
7 citations