Sandip Mandal

DNA Nanocage-Mediated Aspirin Delivery Mitigates Excitotoxicity and Promotes Neuroprotection in Ischemic Stroke-Induced Zebrafish

This paper demonstrates that DNA nanocages delivering aspirin reduce excitotoxicity and promote neuroprotection in zebrafish models of ischemic stroke.

In silico self-assembly and complexation dynamics of cationic lipids with DNA nanocages to enhance lipofection

This study uses MD simulations to investigate how cationic lipids interact with DNA nanocages to enhance drug delivery efficiency.

AT vs. GC binding of protamine-template: A microscopic understanding through molecular dynamics and binding free energies

This study uses molecular dynamics simulations to show that a protamine-mimicking peptide binds preferentially to GC-rich sequences in the major groove and AT-rich sequences in the minor groove of DNA.

Mechanistic Insights into Crossover-Dependent Stability and Exceptional Resistance of PX/JX Nanostructures to DNase I using Enhanced Sampling

This study uses enhanced sampling to reveal how crossover points in PX/DNA structures enhance nuclease resistance by altering helix topology and reducing DNase I binding affinity.