Jake R. Conway

The paper introduces BEANIE, a nonparametric method to improve differential enrichment analysis in single-cell transcriptomics by accounting for sample-specific biology and robustness of signatures across cohorts.

This paper reports a case where platinum chemotherapy exposure was linked to the development of aggressive thyroid cancer through mutational signatures and genomic analysis.

UpSetR provides a scalable matrix-based visualization for intersecting sets and their properties, offering an alternative to Venn and Euler diagrams.