Impact of gestational low-protein intake on embryonic kidney microRNA expression and in the nephron progenitor cells of the male offspring fetus
Letícia de Barros Sene, Íscia Lopes‐Cendes, Wellerson Rodrigo Scarano, Adriana Zapparoli, José Antônio Rocha Gontijo, Patrícia Aline Boer
This study shows that gestational low-protein diet alters miRNA expression and nephron progenitor cell dynamics in fetal male offspring, leading to reduced nephron numbers and renal dysfunction.
PLoS ONE · Feb 5, 2021Peer-reviewedDevelopmental Biology