Single-Cell Analysis of Meningiomas Reveals Mutation-Associated Tumor and Immune Cell Gene Expression Programs
José Maldonado, Bryce L. Mashimo, Anthony Z. Wang, Rupen R. Desai, Saad M. Khan, Ngima D. Sherpa, Markus I. Anzaldua-Campos, Gregory Joseph Zipfel, Albert H. Kim, Joshua L. Dowling, Eric C. Leuthardt, Joshua William Osbun, Ananth Kesav Vellimana, Michael R. Chicoine, Gavin P. Dunn, Allegra A. Petti
This study uses single-cell and spatial transcriptomics to identify mutation-associated gene expression programs in meningiomas, linking genetic alterations to tumor and immune cell states.
bioRxiv · May 21, 2025 · PreprintCancer Biology