Author

José Maldonado

Harvard UniversityORCID 0009-0002-8536-3101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Allegra A. PettiiD· 2 shared Anthony Z. WangiD· 2 shared Gavin P. DunniD· 2 shared Albert H. KimiD· 1 shared Ananth Kesav VellimanaiD· 1 shared Bryce L. MashimoiD· 1 shared Cameron M. HilliD· 1 shared Carlo D. CristobaliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Allegra A. PettiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells

Jia-Shiun Leu, Hui Deng, Han Nhat Tran, Wei Xiong, Nourhan Abdelfattah, Thomas K. S. Wong, Reece Kang, Chihiro Hashiomoto, Fransisca Leonard, Sinem Gunalp, José M. Benítez Salazar, José Maldonado, Carlo D. Cristobal, Hyun Kyoung Lee, Zhiqiang An, , Kyuson Yun

This study shows that combining S100A4 and TIGIT inhibition suppresses breast cancer lung metastasis by enhancing T and NK cell activity in late-stage disease.

Cancer Letters · Apr 8, 2026Peer-reviewedCancer Biology

Mapping CD4+ T Cell Landscapes in Glioblastoma Reveals Effectors and Bystanders

Cameron M. Hill, Anthony Z. Wang, José Maldonado, Tanner Michael Johanns, Allegra A. Petti, Gavin P. Dunn

The paper maps CD4+ T cell landscapes in glioblastoma, revealing effector and bystander populations with distinct clonal and transcriptional features across tumor and blood compartments.

bioRxiv · Sep 25, 2025 · PreprintImmunology

Single-Cell Analysis of Meningiomas Reveals Mutation-Associated Tumor and Immune Cell Gene Expression Programs

José Maldonado, Bryce L. Mashimo, Anthony Z. Wang, Rupen R. Desai, Saad M. Khan, Ngima D. Sherpa, Markus I. Anzaldua-Campos, Gregory Joseph Zipfel, Albert H. Kim, Joshua L. Dowling, Eric C. Leuthardt, Joshua William Osbun, Ananth Kesav Vellimana, Michael R. Chicoine, Gavin P. Dunn, Allegra A. Petti

This study uses single-cell and spatial transcriptomics to identify mutation-associated gene expression programs in meningiomas, linking genetic alterations to tumor and immune cell states.

bioRxiv · May 21, 2025 · PreprintCancer Biology