Identification of proteins exhibiting in vitro RNA chaperone activity through gradient profiling in the Lyme disease spirochete, Borrelia burgdorferi
Taylor J. Van Gundy, Cornelius Schneider, Christopher C. Ebmeier, Gavin Z. Chambers, Nick Cramer, Kathryn Flinn, Dan Drecktrah, Jenny A. Hyde, Jon T. Skare, Richard T. Marconi, D. Scott Samuels, Meghan C. Lybecker
The paper identifies RNA chaperone proteins in Borrelia burgdorferi using gradient profiling and validates their RNA-binding activity through in vitro and in vivo assays.
bioRxiv · Sep 19, 2025 · PreprintMolecular Biology