Christopher C. Ebmeier

This study identifies an antisense oligonucleotide that selectively modulates -1 ribosomal frameshifting of the PEG10 gene by targeting its RNA pseudoknot structure.

The paper identifies RNA chaperone proteins in Borrelia burgdorferi using gradient profiling and validates their RNA-binding activity through in vitro and in vivo assays.

This study identifies CDK7-dependent mechanisms regulating RNAPII function at gene 5'- and 3'-ends through biochemical reconstitution and multi-omics analysis.

This study shows that Burmese pythons can sustain cardiac growth through cardiomyocyte hyperplasia by re-entering the cell cycle after frequent feeding.

The paper identifies CaMKIIδ-B subcellular localization as a determinant of myocardial recovery in heart failure, showing cytoplasmic retention impairs recovery.

This study shows that cyanoexosortase B (CrtB) is essential for motility, biofilm formation, and scytonemin production in Nostoc punctiforme.

This study identifies FoxO1-dependent autophagy as a conserved mechanism for regression of physiological cardiac hypertrophy across species.

This paper introduces a DLP-based 3D printing method for rapid, high-efficiency fabrication of human engineered heart tissues to model cardiac disease.

This study shows CBD disrupts cholesterol homeostasis in human cell lines, altering metabolites, transcripts, and proteins related to cholesterol biosynthesis, transport, and storage.

The paper develops a stapled peptide that inhibits p53-Mediator interaction, suppressing p53 transcriptional activity in cancer cells.

The paper identifies and functionally characterizes MIPs lost in RIB72A/B knockout Tetrahymena cells using proteomics and cryo-electron tomography.

The paper identifies nuclear interactors of DYRK1A, revealing its role in DNA damage repair and providing a resource for further functional studies.

This study uses cerebral organoid proteomics to identify dysregulated networks in trisomy 21 and shows harmine partially normalizes key developmental regulators.