L. Elaine Epperson

Genomic sequence characteristics and the empiric accuracy of short-read sequencing

The paper evaluates short-read variant calling accuracy in Mycobacterium tuberculosis using Illumina and PacBio data, finding high precision with optimized mapping thresholds and identifying 68% of excluded repetitive regions as accurately called.

In-host population dynamics of M. tuberculosis during treatment failure

The paper analyzes M. tuberculosis population dynamics during treatment failure using whole-genome sequencing data from clinical isolates to identify resistance mutations and in-host evolutionary patterns.

Genetic architecture drives seasonal onset of hibernation in the 13-lined ground squirrel

The paper identifies genetic loci associated with the seasonal onset of hibernation in 13-lined ground squirrels, finding high heritability and significant associations with genes involved in energy homeostasis and insulin signaling.