The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal cord injury in male mice
Carlos A. Toro, Jens Hansen, Mustafa M. Siddiq, Kaitlin Johnson, Wei Zhao, Daniella Azulai, Dibash Kumar Das, William A. Bauman, Robert Sebra, Dongming Cai, Ravi Iyengar, Christopher P. Cardozo
This study shows that the ApoE4 variant in mice leads to worse recovery and reduced neuronal sprouting after spinal cord injury compared to ApoE3.
Frontiers in Cellular Neuroscience · Feb 18, 2021Peer-reviewedNeuroscience