Christopher P. Cardozo

This paper introduces an implantable poly(pro-curcumin) film that provides long-lasting neuroprotection after spinal cord injury by locally delivering curcumin, improving locomotor recovery and reducing inflammation.

This study shows that inhibiting HuR with SRI-42127 reduces neuroinflammation and improves functional outcomes after spinal cord injury.

This study shows that oral boldine reduces neuropathic pain in mice by inhibiting inflammation and glial activation.

The paper compares transcriptional responses to resistance exercise in rats and mice, finding conserved pathways but species-specific differences in energy metabolism.

This study identifies a four-drug combination that promotes axonal regeneration in the optic nerve of rats by targeting subcellular processes, leading to functional recovery.

The paper identifies SCI-induced changes in axonal RNA, including circular RNAs, and shows that reducing ADAR1 promotes axonal outgrowth.

Boldine improves locomotor function and reduces glial activation in a mouse model of spinal cord injury by modulating calcium signaling and gene expression.

This study uses RNA-sequencing to identify age-associated gene expression changes in skeletal muscle of mice after laparotomy, showing the greatest effects in younger mice.

The paper identifies extracellular histones as new inhibitors of CNS axonal regeneration, showing they induce growth cone collapse and can be reversed by activated protein C.

This study shows that the ApoE4 variant in mice leads to worse recovery and reduced neuronal sprouting after spinal cord injury compared to ApoE3.