Author

Valeri I. Vasioukhin

Fred Hutch Cancer CenterORCID 0000-0002-6730-0281Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Armand Bankhead· 1 shared Brian P. HanrattyiD· 1 shared Bruce MontgomeryiD· 1 shared Colin C. PritchardiD· 1 shared Colm M. MorrisseyiD· 1 shared Dapei LiiD· 1 shared Divin Wilson· 1 shared Dmytro RudoyiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Armand Bankhead

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies

Sander B. Frank, Thomas W. Persse, I. M. Coleman, Armand Bankhead, Dapei Li, Navonil De Sarkar, Divin Wilson, Dmytro Rudoy, Manasvita Vashisth, Patty Galipeau, Michael Yang, Brian P. Hanratty, Ruth F. Dumpit, Colm M. Morrissey, Eva Corey, , Peter S. Nelson

This study shows that acute CDK12 loss in prostate cancer causes HR deficiency via polyadenylation, but chronic loss leads to adaptation, making PARP inhibitors ineffective and suggesting CDK13 targeting as a new therapeutic approach.

bioRxiv · Jul 16, 2024 · PreprintCancer Biology