Cell BiologyNature CommunicationsPeer-reviewed
Architecture of intact mammalian pyruvate dehydrogenase complex revealed by in-situ structural analysis
Chen Wang, Cheng Ma, Yuanyou Xu…·Yunjie Chang
This study reveals the in-situ architecture of the mammalian pyruvate dehydrogenase complex using cryo-electron tomography, showing dynamic interactions and variable peripheral compositions.