Author

Jeffrey L. Brabec

University of VermontORCID 0000-0002-6740-4582Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

J. Matthew MahoneyiD· 2 shared Amanda E. HernaniD· 1 shared Anna L. TyleriD· 1 shared Mohamed OuardouziD· 1 shared Montana Kay LaraiD· 1 shared Rod C. ScottiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersGenetics

J. Matthew MahoneyORCID

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2 papers

Recent·Most cited

A multi-network approach to Alzheimers Disease gene prioritization complements cis-regulatory prioritization with molecular quantitative trait loci

Jeffrey L. Brabec, Montana Kay Lara, Anna L. Tyler, J. Matthew Mahoney

This paper introduces a multi-network gene prioritization method for Alzheimer's Disease that complements mQTL-based approaches, showing significant concordance in prioritizing risk genes.

bioRxiv · May 3, 2023 · PreprintGenetics

Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizures

Jeffrey L. Brabec, Mohamed Ouardouz, J. Matthew Mahoney, Rod C. Scott, Amanda E. Hernan

The paper investigates how ACTH and dexamethasone affect gene expression pathways in rats after early-life seizures, showing ACTH normalizes expression while Dex does not.

Neurobiology of Disease · Sep 21, 2022Peer-reviewedNeuroscience