Amanda E. Hernan

The paper uses bag-of-waves classifiers to predict epilepsy genotypes in mice from EEG data, achieving high accuracy and specificity.

This paper identifies novel epilepsy modifier genes in mice through meta-analysis of GWAS data and functional network analysis, highlighting genes involved in neurodevelopmental processes not targeted by current therapies.

This study shows that developmental insults impair mPFC network dynamics, and ACTH treatment prevents these impairments, preserving cognitive function through restored network organization.

This study shows ACTH prevents anxiety-like behaviors and normalizes astrocyte proteins after early life seizures via MC4R activation in neurons and astrocytes.

This study examines how Fmr1 knockout rats exhibit behavioral and neural network impairments linked to autism-like symptoms, suggesting that restoring neural dynamics may improve outcomes.

The paper investigates how ACTH and dexamethasone affect gene expression pathways in rats after early-life seizures, showing ACTH normalizes expression while Dex does not.

The paper investigates how spatial working memory is encoded and maintained in the hippocampal-prefrontal network using single-unit recordings in rats, finding altered dynamics in a disease model.

The paper shows environmental enrichment improves cognitive function in rats with hippocampal malformations by restoring abnormal spike timing and rate coding in hippocampal neurons.