Scott T. Wood

Microfluidic Osteoarthritis-on-a-Chip for Evaluating Joint-Cell Responses to Tanezumab, a Humanized Anti-NGF Monoclonal Antibody

This study evaluates tanezumab's effects on joint cells using a microfluidic co-culture system, revealing differential biomarker responses compared to monoculture.

Microfluidic Osteoarthritis-on-a-Chip: Modeling Human Joint Inflammation

This paper develops a microfluidic joint-on-a-chip model to study OA inflammation, showing enhanced MMP expression in co-cultures but not full inflammatory mediator recapitulation.

Microfluidic Co-Culture for Modeling Human Joint Inflammation in Osteoarthritis Research

This paper presents a microfluidic co-culture system that models human joint inflammation in osteoarthritis by co-culturing multiple cell types and shows increased metabolic activity and viability in both healthy and diseased conditions.