Mutations in the riboflavin biosynthesis pathway confer resistance to furazolidone and abolish the synergistic interaction between furazolidone and vancomycin in Escherichia coli.
Hannah Wykes, Vuong Van Hung Le, Jasna Rakonjac
The paper identifies mutations in riboflavin biosynthesis genes that confer resistance to furazolidone and reduce synergy with vancomycin in E. coli.
Microbial Genomics · Feb 11, 2025Peer-reviewedMicrobiology