Paraskevas Filippidis

scCRAFT+ improves scRNA-seq integration by incorporating marker gene information via virtual adversarial training, enhancing accuracy and robustness to noisy annotations.

The paper uses scRNA-seq to analyze T cell responses in cutaneous Lyme disease, identifying CD8+ GZMK+ IFNG+ T cells as a key immune population with inflammatory properties.

The paper introduces scCRAFT, an autoencoder for scRNA-seq batch integration that outperforms existing methods by preserving biological heterogeneity and handling unbalanced batches and rare cell types.