Jian Xing

An Open Benchmark for Systems Vaccinology: Insights from the CMI-PB Challenges

The paper benchmarks computational models predicting B. pertussis booster vaccine responses using multi-omics data from three cohorts, identifying key predictors of immunity and establishing a community resource for systems vaccinology.

Assessing tensor decomposition quality of immune profiling data from a dictionary learning perspective

The paper introduces metrics for assessing tensor decomposition quality in immune profiling data using a dictionary learning framework.

Robust semi-supervised scRNA-seq integration from virtual adversarial learning

scCRAFT+ improves scRNA-seq integration by incorporating marker gene information via virtual adversarial training, enhancing accuracy and robustness to noisy annotations.

Post-injury born oligodendrocytes integrate into the glial scar and inhibit growth of regenerating axons by premature myelination

The paper investigates how post-injury born oligodendrocytes integrate into the glial scar and inhibit axon regeneration by premature myelination.

CellTools algorithm for mapping scRNA-seq query cells to the reference dataset improves the classification of resilient and susceptible retinal ganglion cell types

The paper introduces CellTools, an algorithm that improves scRNA-seq cell mapping and classification, revealing new insights into retinal ganglion cell resilience to injury.