Joakim Näsvall

This study shows that point mutations in multiple genes can restore tryptophan biosynthesis in Salmonella enterica lacking trpF, demonstrating bifunctional genetic solutions without gene duplication.

This study shows that reducing tRNA pool size in Salmonella enterica leads to compensatory mutations that increase translation speed over accuracy, highlighting translation rate as a key evolutionary pressure.

This paper introduces a new lambda Red recombineering method called DIRex for generating precise bacterial gene mutations without scars or resistance markers.