The centrosomal protein 83 (CEP83) regulates human pluripotent stem cell differentiation towards the kidney lineage
Fatma Mansour, Christian Hinze, Narasimha Swamy Telugu, Jelena Kresoja‐Rakic, Iman B. Shaheed, Christian Mosimann, Sebastian Diecke, Kai Martin Schmidt-Ott
This study shows that CEP83 deficiency in hiPSCs disrupts intermediate mesoderm differentiation, leading to impaired kidney progenitor formation and increased LPM marker expression.
eLife · Oct 12, 2022Peer-reviewedDevelopmental Biology