Afadin-deficient mouse retinas exhibit severe neuronal lamination defects but preserve visual functions
Akiko M. Ueno, Konan Sakuta, Ono H, Aki Hashio, Haruki Tokumoto, Mikiya Watanabe, Taketo Nishimoto, Toru Konishi, Yuki Emori, Shunsuke Mizuno, Mao Hiratsuka, Jun Miyoshi, Yoshimi Takai, Masao Tachibana, Chieko Koike
This study shows that afadin deficiency in mice causes severe retinal lamination defects but preserves some visual function through retained local field potentials and RGC classification.
eLife · Dec 22, 2025Peer-reviewedNeuroscience