David J. Evans

Prior contact lens wear reduces susceptibility of the superficially-injured cornea to bacterial adhesion

The paper shows that prior contact lens wear reduces bacterial adhesion to superficially-injured corneas in mice, correlating with increased Lyz2+ immune cells, but with differing effects on commensal and pathogen behavior.

Cross-membrane cooperation among bacteria can facilitate intracellular pathogenesis

This study shows that Pseudomonas aeruginosa subpopulations cooperate through Ca2+ influx via T3SS to transition from vacuoles to cytoplasm and disseminate in vivo.

TRPV1 Defends the Healthy Murine Cornea against Staphylococcus aureus Adhesion Independently of Sensory Nerve Firing

This study shows TRPV1 protects murine corneas from S. aureus adhesion without requiring sensory nerve firing, unlike its role against P. aeruginosa.

The Pseudomonas aeruginosa T3SS can contribute to traversal of an in situ epithelial multilayer independently of the T3SS needle

This study shows that Pseudomonas aeruginosa can traverse a multilayered epithelium using T3SS effectors and translocon proteins without the T3SS needle.

Contact Lens Wear Alters Transcriptional Responses to Pseudomonas aeruginosa in Both the Corneal Epithelium and the Bacteria

This study shows that contact lens wear changes corneal epithelium and bacterial gene expression responses to Pseudomonas aeruginosa, promoting bacterial virulence and adaptation.