SARS-CoV-2's evolutionary capacity is mostly driven by host antiviral molecules
Kieran D. Lamb, Martha M. Luka, Megan Saathoff, Richard J Orton, My V. T. Phan, Matthew L. Cotten, Ke Yuan, David L. Robertson
The paper uses machine learning to identify mutational signatures in SARS-CoV-2 genomes and links them to host antiviral molecules, showing these drive most of the virus's evolutionary changes.
bioRxiv · Apr 7, 2023 · PreprintGenomics