Richard J Orton

This study identifies cross-neutralizing mAbs against diverse bat sarbecoviruses and characterizes their conserved epitopes for vaccine design.

The paper identifies manufacturing plasmid sequences and disrupted vector genomes in liver tissue from a patient with AAV gene therapy-related hepatitis.

This study expands the known diversity of human anelloviruses by analyzing 829 genomes from microbiome datasets and identifies new clades and recombination patterns.

The paper uses machine learning to identify mutational signatures in SARS-CoV-2 genomes and links them to host antiviral molecules, showing these drive most of the virus's evolutionary changes.

The paper quantifies unknown sequences in human microbiomes, finding 2% on average are taxonomically undefined, with higher rates in skin and oral microbiomes.