Genetic dissection of the mitochondrial lipoylation pathway in yeast
Laura P. Pietikäinen, Mahbubur Rahman, J. Kalervo Hiltunen, Carol L. Dieckmann, Alexander J. Kastaniotis
The paper characterizes the mitochondrial lipoylation pathway in yeast, showing it can use free lipoic acid and octanoic acid as substrates when activating enzymes are mitochondrial-targeted, and reveals conserved features in mammalian mitochondria.
BMC Biology · Jan 24, 2021Peer-reviewedMolecular Biology