GRK2-mediated AKT activation controls cell cycle progression and G2-checkpoint in a p53-dependent manner
Verónica Rivas, Teresa González-Muñoz, Ángela Albitre, Vanesa Lafarga, Cristina Delgado‐Arévalo, Federico Mayor, Petronila Penela
This study identifies GRK2's role in regulating AKT activation during the G2/M transition, showing its dependence on p53 for checkpoint control and tumor cell survival.
Cell Death Discovery · Aug 28, 2024Peer-reviewedMolecular Biology