Author

Zhiqin Huang

German Cancer Research CenterORCID 0000-0002-6958-4900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Marc ZapatkaiD· 2 shared Alexander Jethwa· 1 shared Benedikt BrorsiD· 1 shared Birgit Burkhardt· 1 shared Christiane Pott· 1 shared consortium MMML· 1 shared David JonesiD· 1 shared Donato Tedesco· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Marc ZapatkaORCID

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2 papers

Recent·Most cited

MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma

Jennifer Hüllein, Mikołaj Słabicki, Maciej Rosolowski, Alexander Jethwa, Stefan Habringer, Katarzyna Tomska, Roma Kurilov, Junyan Lu, Sebastian Scheinost, Rabea Wagener, Zhiqin Huang, Marina Lukas, Olena Yavorska, Hanne Helferich, René Scholtysik, , Thorsten Zenz

This study identifies MDM4 as a critical target of 1q gain in TP53wt Burkitt lymphoma, showing its role in evading cell cycle arrest and highlighting its therapeutic potential.

bioRxiv · Apr 9, 2018 · PreprintCancer Biology

confFuse: high-confidence fusion gene detection across tumor entities

Zhiqin Huang, David Jones, Yonghe Wu, Peter Lichter, Marc Zapatka

confFuse identifies high-confidence fusion genes from RNA-seq data by scoring candidates based on structural motifs, reducing false positives while maintaining high accuracy.

Frontiers in Genetics · Sep 29, 2017Peer-reviewedBioinformatics