Peter Lichter

The paper identifies extracellular glutathione catabolism as a driver of metastasis by enabling proliferation and oxidative stress resistance in metabolically challenging microenvironments.

This study uses pan-cancer phosphoproteomics to identify therapeutic targets and improve precision oncology by analyzing 1,998 tumor samples and developing new scores for kinase activity and immune response.

This paper introduces a method to generate localized DNA double-strand breaks in cell populations using UV-irradiation with photomasks, enabling the study of genome rearrangements and DNA damage response.

confFuse identifies high-confidence fusion genes from RNA-seq data by scoring candidates based on structural motifs, reducing false positives while maintaining high accuracy.

This study identifies ALT markers and mechanisms in pediatric glioblastoma using genomic and telomere features, revealing non-canonical ALT and a reliable classification scheme.

TelomereHunter estimates and characterizes telomere content from whole genome sequencing data in cancer studies.

This study compares whole genome sequencing pipelines across five centers using a uniform tumor-normal sample pair, identifying factors affecting output consistency.