Jonathan A. White

The paper presents a method to decode overlapping barcodes in spatial genomics with low false discovery rate, enabling super-resolution microscopy through coded barcodes.

This study uses high-resolution spatial multi-omics to analyze subnuclear compartments in single cells, revealing cell-type specific chromatin structures and their genomic associations.

The paper uses integrated spatial genomics to study nuclear architecture in mouse brain cortex cells, revealing chromatin fixed points and cell-type specific organization of nuclear bodies.

The paper maps chromatin states, DNA loci, and gene expression in single mouse embryonic stem cells using DNA seqFISH+ and immunofluorescence, revealing nuclear zones and subpopulations with distinct chromatin features.