Systems BiologyNature GeneticsPeer-reviewed
Desmosome mutations impact the tumor microenvironment to promote melanoma proliferation
Maayan Baron, Mohita M. Tagore, Patrick Wall…·Trey E. Ideker
The paper shows that desmosome mutations in keratinocytes of the tumor microenvironment promote melanoma proliferation through reduced desmosome gene expression and increased melanoma cell growth.
8 citations