Author

Carlos A Z Bassetto

The University of Texas at San AntonioORCID 0000-0002-7012-5699Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:electrophysiology· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Francisco BezanillaiD· 2 shared Bernardo I. PintoiD· 1 shared Eduardo PerozoiD· 1 shared Gustavo F. ContrerasiD· 1 shared Ramón LatorreiD· 1 shared Yichen LiuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersBiophysics

Francisco BezanillaORCID

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2 papers

Recent·Most cited

Closed State Structure of the Pore Revealed by Uncoupled Shaker K+ Channel

Yichen Liu, Carlos A Z Bassetto, Gustavo F. Contreras, Eduardo Perozo, Francisco Bezanilla

The paper reveals the closed state structure of the Shaker K+ channel by uncoupling voltage sensor domains, showing a novel 'roll and turn' movement of S6 helices and a noncanonical selectivity filter state.

Nature Communications · Nov 19, 2025Peer-reviewedBiophysics

Turning a Kv channel into hot and cold receptor by perturbing its electromechanical coupling.

Bernardo I. Pinto, Carlos A Z Bassetto, Ramón Latorre, Francisco Bezanilla

This study shows that a single mutation can drastically alter the temperature response of Kv channels by modifying their electromechanical coupling.

Nature Communications · Apr 9, 2025Peer-reviewedBiophysics