NeurosciencebioRxivPreprint
Sympathetic Nervous System Overactivation Induces Colonic Eosinophil-Associated Microinflammation and Contributes to the Pathogenesis of Irritable Bowel Syndrome
Shaoqi Duan, Hirosato Kanda, Feng Zhu…·Yi Dai
This study shows that sympathetic nervous system overactivation in a maternal separation model leads to colonic eosinophil infiltration and visceral hypersensitivity, contributing to IBS pathogenesis.
DOI 10.1101/2024.07.22.604223