Author

Jakob C Green

Virginia Commonwealth UniversityORCID 0000-0002-7059-9173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Dong SuniD· 2 shared Alexandra Pedin· 1 shared Christopher Nelson· 1 shared Chunqing GuoiD· 1 shared Nicole M. WestoniD· 1 shared Sarah A. BaigiD· 1 shared Sarah Timis· 1 shared Shijun ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Dong SunORCID

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2 papers

Recent·Most cited

Deletion of NLRP3 gene blocks traumatic brain injury induced abnormal immune response in 3xTg AD mice

Jakob C Green, Zheng Liu, Sarah Timis, Christopher Nelson, Alexandra Pedin, Chunqing Guo, Xiang-Yang Wang, Shijun Zhang, Dong Sun

This study shows that deleting the NLRP3 gene reduces TBI-induced immune changes in 3xTg AD mice, but only in males, highlighting sex-related differences.

bioRxiv · Apr 28, 2026 · PreprintImmunology

Traumatic brain injury has a lasting impact on hippocampal neurogenesis and Notch1 is involved in regulating this injury response

Nicole M. Weston, Timothy N Keoprasert, Jakob C. Green, Sarah A. Baig, Dong Sun

This study investigates how traumatic brain injury affects hippocampal neurogenesis and shows that Notch1 regulates this response by influencing neural stem cell proliferation and differentiation.

bioRxiv · Feb 5, 2026 · PreprintNeuroscience